Secondhand smoke exposure effect on elastin degradation markers: which factors should be taken into account?

Affi liations: From the Section of Pulmonary and Critical Care Medicine, Asthma Clinical Research Center (Dr Hanania), Baylor College of Medicine; Division of Pulmonary and Critical Care Medicine (Dr Celli), Brigham and Women’s Hospital, Harvard University; Division of Pulmonary Disease and Critical Care Medicine (Dr Donohue), University of North Carolina at Chapel Hill; and Clinical Research, Respiratory and Infl ammation Therapeutic Area (Dr Martin), AstraZeneca LP. Financial/nonfi nancial disclosures: The authors have reported to CHEST the following confl icts of interest: Dr Hanania has received research grant support from Boehringer Ingelheim, AstraZeneca, GlaxoSmithKline, Novartis, and Pfi zer and has served as a consultant for GlaxoSmithKline, Novartis, and Pfi zer and on the Speakers Bureaus of GlaxoSmithKline, Boehringer Ingelheim, and AstraZeneca. Dr Celli has received grants from GlaxoSmithKline, Boehringer Ingelheim, Forrest Medical, and AstraZeneca to the division he heads to complete research studies. He has received advisory board payments from GlaxoSmithKline, Boehringer Ingelheim, Almirall, and AstraZeneca. Dr Donohue has received grant monies from Boehringer Ingelheim, Novartis, Johnson & Johnson, National Institutes of Health, and Alpha-1 Foundation, has served as a consultant for Novartis, AstraZeneca, Boehringer Ingelheim, GlaxoSmithKline, Pfi zer, and Merck, and has participated in speaking activities for Boehringer Ingelheim, Pfi zer, GlaxoSmithKline, and AstraZeneca. Dr Martin is a salaried employee at AstraZeneca LP holding company and receives shares/stock as part of a compensation package . Correspondence to: Nicola A. Hanania, MD, FCCP, Baylor College of Medicine, 1504 Taub Loop, Houston, TX 77030; e-mail: [email protected] © 2012 American College of Chest Physicians. Reproduction of this article is prohibited without written permission from the American College of Chest Physicians ( http :// www . chestpubs . org / site / misc / reprints . xhtml ). DOI: 10.1378/chest.12-0231